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硕士生导师

姚团利

2017年11月13日 17:15  点击:[]

姓名

姚团利

性别

出生年月

1970.11

民族

籍贯

陕西

最高学位

博士

职称/职务

三级教授

联系

方式

电话

15249093699

邮箱

yaotuanli@sust.edu.cn

学习经历

1999-2005, 美国爱荷华州立大学(Iowa State University, 有机化学博士

1994-1997, 北京大学, 硕士

1988-1992, 北京大学, 学士

工作经历

2014-现在,  陕西科技大学化学与化工学院, 教授

2009-2014, 美国堪萨斯大学University of Kansas)专业化学中心(Specialized Chemistry Center), Associated Researcher

2006-2009, 美国Deciphera Pharmaceuticals, Inc., Senior Scientist- Chemistry

2005-2006, 美国加州伯克利大学(UC Berkeley), 博士后

1992-1994, 西安近代化学研究所,助理研究员

研究方向

1. 发展新型高效的化学方法应用于重要杂环小分子的构建和具有生理活性的天然产物的全合成,及其在抗病毒、抗菌药物研发上的筛选应用

2. 具有高生物活性小分子的化学合成及其在化学生物学研究中的应用。

承担的主

要项目及

成果

获奖

2016入选陕西省百人计划创新全职项目

项目

   2015年以来,先后主持陕西科技大学高层次人才科研启动基金/陕西省自然科学基金/企业横向课题等项目10多项。

发表论文情况

60. Yao, T.*; Liu, W.; Hu, H. F.; Qin, X. * “Synthesis of continuously substituted quinolines from o-alkenyl aromatic isocyanides by palladium-catalyzed intramolecular imidoylative 6-endo cyclization”, Chem Commun. 2025, 61, 1399.(自然指数期刊)

59. Yao, T.*; She, J, E.; Li, T*.; Qin, X.* “Highly Regio- and Diastereoselective Synthesis of 6,7-Dihydro-4H-furo[3,4-c]pyran Derivatives through Pd-Catalyzed Formal (3 + 3) Allylic Cycloaddition of 2-Butene-1,4-diols with 2-(1-Alkynyl)-2-alken-1-ones”, Org Lett, 2024, 26, 2018.SCI一区TOP,自然指数期刊)

58. Yan, Q.; Zhuang, Z.; Fan, R.; Wang, J.; Yao, T.*;, Tan, J.* “Access to N-Aryl (Iso)quinolones via Aryne-Induced Three-Component Coupling Reaction”, Org Lett, 2024, 26, 1840.SCI一区TOP,自然指数期刊)

57. Yao, T.*;, Wang, K.; Zhu, S.; Li T.* Mn(acac)3诱导1-异腈基-2-[1-(三氟甲基)乙烯基]苯自由基环化合成4-三氟甲基喹啉衍生物” 高等学校化学学报, 2024, 45, 20230448.(自然科学类领军期刊)

56. Zhang, X.*; Wang, Y.; Liu, J.; Tian, P.; Li, X.; Xie, P.; Zhu, Z*.; Yao, T.* “Synthesis of 3-aminotetrahydro-1H-carbazols by visible-light photocatalyzed cycloaddition of cyclopropylanilines with 2-alkenylarylisocyanides”, Chem Commun. 2023, 59, 14423.(自然指数期刊)

55. Yao, T.*; Zhu, R.; Liu, T. “Synthesis of 3-aminoindenes and cis-1-aminoindanes by Zn(OTf)2-catalyzed cyclization of o-alkynylbenzaldehydes with tertiary alkyl primary amines”, Chem Commun. 2023, 59, 14325.(自然指数期刊)

54. Liu, T.; Yao, T.*; Guo, R.*; Qin, X.* “Palladium-catalyzed cascade cyclization /intramolecular redox-relay Heck arylation of alkenols: access to tetrahydro-β-carbolines from 2-(hydroxyalkenynyl)sulfonanilides”, Org. Chem. Front. 2023, 10, 3504.SCI一区TOP)

53. Yao, T.*; Zhu, S.; Qin, X.* Manganese-catalyzed synthesis of 4-CF3-2-phosphinoylquinolines via radical 6-endo-trig cyclization of 1-Isocyano-2-(1-(trifluoromethyl)ethenyl)benzenes, Tetrahedron Lett, 2023, 121.

52. Yao, T.*; Jiao, T. Nickel-Catalyzed Enantioselective Reductive Conjugate Arylation and Heteroarylation via an Elementary Mechanism of 1,4-Addition, 有机化学, 2023, 42, 4362.

51. Li, X.; Zhao, Y.*; Yao, T.; Nan, J.; Zhang, J. “Discussion of Nomenclature: Parent Hydride and Characteristic Group, 大学化学, 2023, 38, 268.

50. Yao, T.*; Zhao, S.; Liu, T.; Wu, Y.; Ma, Y.; Li, T. *; Qin, X*. “Transition-metal-free approaches to 2,3-diarylated indenones from 2-alkynylbenzaldehydes and phenols with tunable selectivity”, Chem. Commun. 2022, 58, 4592.(封面文章,自然指数刊)

49. Liang, J.; Zhang, P.; Yang, H.; Zhang, Y.; Yao, T.; Liu, K.; Wang, Y. *; Zhang, X. *; Qin, X.* “Design, synthesis and biological evaluation of novel nitric oxide donors with antioxidative activity”, Eur. J. Med. Chem. 2022, 236, 114331. SCI一区TOP

48. Liu, T.; Yao, T. *; Zhang, F.; Ju, Y.; Tan, J. * “Cleavage and Reassembly of the C=O Bond of 2-Alkynylbenzaldehydes: A Metal-Free Access to Inden-1-ones” J. Org. Chem. 2021, 86, 9455.SCI二区

47. Yao, T.*; Hui, J.; Liu, T.; Li, T.* Palladium-Catalyzed Three-Component Carbocarbonation of Arynes: Expeditious Synthesis of o-Alkylated Arylacrylates and Stilbenes”, J. Org. Chem. 2021, 86, 5477.SCI二区)

46. Yao, T.*; Wang, B.; Ren, B.; Qin, X.*; Li, T.* Palladium-catalyzed Ugi-type reaction of 2-iodoanilines with isocyanides and carboxylic acids affording N-acyl anthranilamides”, Chem. Commun. 2021, 57, 4247.(自然指数期刊)

45. Yao, T.*; Wang, B.; He, D.; Zhang, X.; Li, X.; Fang, R.* “Ligand-Controlled Palladium-Catalyzed Chemoselective Multicomponent Reaction of Olefin-Tethered Aryl Halides, Isocyanides, and Carboxylic Acids: Diversified Synthesis of ImidesOrg. Lett. 2020, 22, 6784.SCI一区TOP,自然指数期刊)

44. Li, X.*; Zhang, R.; Qi, Y.; Zhao, Q.; Yao, T.* Rhodium(III)-catalyzed C-H activation/annulation of N-iminopyridinium ylides with alkynes and diazo compounds” Org. Chem. Front. 2021, 8, 1190.SCI一区TOP)

43. Guo, Z.; Liu, T.; Liang, X.; Wu, Y.; Yao, T.* Cs2CO3 Catalyzed Intramolecular Aminocarbonylation of Alkynes: Synthesis of 3-Amino-1H-inden-1-ones from N-tert-Butyl-2-(1-alkynyl)benzaldimines” Adv. Synth. Catal. 2020, 362, 1053.SCI一区TOP)

42. Wang, B.; He, D.; Ren, B.; Yao, T.* “Synthesis of imides via palladium-catalyzed three component coupling of aryl halides, isocyanides and carboxylic acids”, Chem. Commun., 2020, 56, 900.自然指数期刊)

41. Zhang, X.*; Zhu, P.; Zhang, R.; Li, X.; Yao, T.* “Visible-Light-Induced Decarboxylative Cyclization of 2-Alkenylarylisocyanides with α-Oxocarboxylic Acids: Access to 2-Acylindoles”, J. Org. Chem. 2020, 85, 9503.SCI二区)

40. Saputra, A.; Fan, R.; Yao, T.*; Chen, J.; Tan, J.* “Synthesis of 2-(Arylthio)indolenines via Chemoselective Arylation of Thio-Oxindoles with Arynes”, Adv. Synth. Catal. 2020, 362, 2683.SCI一区TOP)

39. Yao, T. *; Liang, X.; Guo, Z.; Dong, Y. “Highly stereoselective synthesis of (Z)-3-methoxy-1-methyleneisoindoles via DMAP catalyzed cyclization of methyl 2-alkynylbenzimidates”, Tetrahedron Lett. 2019, 75, 3088.

38. Yao, T. *; Guo, Z.; Liang, X.; Qi, L. “Regio- and Stereoselective Electrophilic Cyclization Approach for the Protecting-Group-Free Synthesis of Alkaloids Lennoxamine, Chilenine, Fumaridine, 8-Oxypseudoplamatine and 2-O-Methyloxyfagaronine” J. Org. Chem. 2018, 83, 133370.SCI二区)

37. Yao, T.*; Ren, B.; Zhao, Y. “Highly Selective Synthesis of Dihydrobenzo[d] isoxazoles and Dihydrobenzo[d]oxazoles from Oximes and Arynes via in Situ Generation of Nitrones, Org. Lett. 2017, 19, 3153.SCI一区TOP,自然指数期刊)

36. Yao, T.*; Liu, T.; Zhang, C. “Palladium-catalyzed domino Heck/intermol ecular cross-coupling: efficient synthesis of 4-alkylated isoquinoline derivatives”, Chem. Commun. 2017, 53, 2386.SCI一区TOP,自然指数期刊)

35. Yao, T.*; He, D. “Palladium-Catalyzed Domino Heck/Aryne Carbopalladation/C-H Functionalization:Synthesis of Heterocycle-Fused 9,10-Dihydrophenanthrenes” Org. Lett. 2017, 19, 842.SCI一区TOP,自然指数期刊)

34. Yao, T.*; Zhang, H.*; Zhao, Y. “Synthesis of 9,10-Phenanthrenes via Palladium-Catalyzed Aryne Annulation by o-Halostyrenes and Formal Synthesis of (±)-Tylophorine”, Org. Lett. 2016, 18, 2532.SCI一区TOP,自然指数期刊)



 

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