承担 的主 要项 目及 成果 |
一、科研项目情况： 1. 国家自然科学基金青年基金：含荧光探针和光敏剂的超分子超支化聚合物的构筑及其诊疗一体化研究，30万元，主持； 2. 陕西科技大学青年拔尖人才启动基金：拓扑聚合物的构筑及其自组装性能研究，60万元，主持； 3. 陕西省科技厅基础科研计划，主客体作用构筑胞内氧化还原水平可调的超分子组装体及其诊疗一体化，5万元，主持； 4. 陕西省教育厅专项科研计划项目：环境响应性长链超分子超支化聚合物的构筑及其药物控释机理研究，2万元，主持； 5. 横向项目：粘合剂动态力学性能及加载性能研究，10万元，主持 6. 横向项目：3D打印用改性甲阶酚醛树脂的研究与开发，5万元，主持 7. 横向项目：可逆形状记忆聚合物设计与开发，4万元，主持 二、学生培养情况： 1. 研究生安娜的研究论文（Carbohydrate Polymers, 2020, 231,115714.），潘玉洁的研究论文（Chinese Chemical Letters, 2023, 34, 107552.）(曾)入选ESI高被引论文 2. 指导研究生李西华获2023年研究生国家奖学金 3. 指导研究生尚青青获2022年研究生国家奖学金 4. 指导研究生安娜获2020年研究生国家奖学金 5. 指导研究生刘彩萍获2019年研究生国家奖学金 6. 指导研究生潘玉洁、靖众等获第11届中国高分子材料创新创业大赛三等奖 7. 指导研究生吴静、尚青青等获第10届中国高分子材料创新创业大赛三等奖 8. 指导本科生谢松霖、李淼等获第10届中国高分子材料创新创业大赛三等奖 9. 指导研究生尚青青获2023年陕西科技大学优秀硕士毕业论文 10. 指导研究生吴静获2023年陕西科技大学优秀硕士毕业论文 11. 指导研究生安娜获2021年陕西科技大学优秀硕士毕业论文 12. 指导研究生刘彩萍获2020年陕西科技大学优秀硕士毕业论文 三、发表论文与专利情况： 已发表论文70余篇，其中以第一作者/通讯作者在Nano Research, ACS Applied Materials & Interfaces (4篇), Advanced Healthcare Materials, Macromolecules, Carbohydrate Polymers (3篇), Journal of Colloid and Interface Science, Journal of Materials Chemistry B (2篇)，Chinese Chemical Letters, Polymer Chemistry (3篇), Polymer (2篇)，ACS Applied Polymer Materials (2篇), Chemistry- an Asian Journal等国际高分子材料顶级刊物发表论文40余篇。 授权并转让3项专利（2项3D打印酚醛树脂领域专利和1项药物分子发明专利）。 课题组主要致力于超分子与功能高分子材料的设计及其在生物医用、柔性电子领域的研究，欢迎有创新精神，勤奋刻苦的学生和我们一起做有趣的研究！代表论文如下（*为通讯作者，详见课题组网页：baiyang.polymer.cn） 2023年： 1. Bai, Y.,* Li, X.H, Song S.J., Yang, J., Liu X., Chen Z.W.* Pillar[6]arene-based supramolecular self-assemblies for two-pronged GSH-consumption-augmented chemo/photothermal therapy. Nano Research. 2023, 16(7), 9921-9929. (IF: 10.269) 2. Liu C.P.#, Bu, H.T.#, Duan X.#, Li H., Bai, Y.* Host-Guest Interactions Based Supramolecular Self-Assemblies for H2O2 Up-Regulation Augmented Chemiluminescence Resonance Energy Transfer Induced Cancer Therapy. ACS Applied Materials & Interfaces. 2023, 15, 38163-39062. (IF：10.383) 3. Bai, Y.,* Yan S.Q., Wang Y.B., Wang Q., Duan X. A facile preparation of self-adhesive conductive hydrogel with long-term usability. ACS Applied Materials & Interfaces. 2023. Accepted (IF：10.383) 4. Bai, Y.,* Liu M.Y., Wang X.N., Liu K., Liu X.P., Duan X. Multi-Functional Nanoparticles for Enhanced Chemodynamic/Photodynamic Therapy through Photothermal, H2O2-Elevation, and GSH-Consumption strategy. ACS Applied Materials & Interfaces. 2023. Accepted (IF：10.383) 5. Bai, Y.,* Wu, J., Liu, K., Wang, X.N., Shang, Q.Q., Zhang, H.T.* Integrated supramolecular nanovalves for photothermal augmented chemodynamic therapy through strengthened amplification of oxidative stress. Journal of Colloid and Interface Science. 2023, 637, 399-407. (IF: 9.9) 6. Bai, Y.,* Pan Y.J., An N., Zhang H.T.,* Wang C., Tian W.,* Huang T. Host-guest interactions based supramolecular complexes self-assemblies for amplified chemodynamic therapy with H2O2 elevation and GSH consumption properties. Chinese Chemical Letters. 2023, 34, 107552. (ESI高被引论文，IF: 9.1) 7. Bai, Y.,* Wang R.Q., Wang X.N., Duan X.*, Yan X.C., Liu C.F.,* Tian W.,* Hyaluronic acid coated nano-particles for H2O2-elevation augmented photo-/chemodynamic therapy. International Journal of Biological Macromolecules. 2023, 245, 125523. (IF: 8.2) 8. Bai, Y.,* Jing Z., Zhang, B.Y., Pan Y.J., Wang Q., Duan X. Recyclable wearable sensor based on tough, self-healing, adhesive polyurethane elastomer for human motions monitoring. ACS Applied Polymer Materials. 2023, 5, 8720-8734. (IF: 5.0) 9. Dai, J.Y., Wang, Z.C., Wu, Z.Z., Fang, Z.Y., Heliu, S.Y., Yang, W.T., Bai, Y.* Shape memory polymer constructed by π-π stacking with ultrafast photoresponse and self-healing performance. ACS Applied Polymer Materials. 2023, 5, 2575-2582. (IF: 5.0) 10. Liu, C.F., Liu, C.P., Bai, Y.,* Wang J.X.*, Tian W*. Drug self-delivery systems: molecule design, construction strategy and biological application. Advanced Healthcare Materials. 2023, 2202769. (IF: 10.0) 11. Wang X.N.#, Wu J.#, Duan X.*, Shang Q.Q., Bai, Y.* Mesoporous silicon based nano-particles for photothermal and H2O2-elevation dually-augmented chemodynamic therapy. Materials Today Nano. Accepted. (IF:10.3) 12. Ma, R., Wang, Y.B., Li, H.*, Bai, Y.* Progress in the polycarboxylate superplasticizer and their structure-activity relationship - A review. Materials Today Communication. 2023, 35, 105838. (IF:3.8) 13. Huang, X.H., Liu S.Y., Rao S.H., Lu J.Y., Xiao K., Bai, Y.,* Huang Z., Li H.*, A fluorescent controllable supramolecular crosslinked polymer constructed by complementary metal coordination interaction. Dalton transactions. Accepted. (IF:4.0) 14. Hu, Q. F., Zhang, H.T.,* Ye, P., Ma S.H., Zhu X.Z., Bai, Y.* Xanthene-based polarity-sensitive fluorescent probe with large Stokes shifts for simultaneous two-color visualizing of lipid droplets and lysosomes. Dyes and Pigments. 2023, 208, 110874. (IF: 5.1) 15. 张勃元，白阳*. 端羟基嵌段共聚醚的制备及其应用研究. 陕西科技大学学报，2023, 5, 87-93. 2022年： 16. Bai, Y.,* Shang, Q.Q., Wu J., Zhang, H.T.,* Liu, C.P., Liu, K. Supramolecular self-assemblies with self-supplying H2O2 and self-consuming GSH property for amplified chemodynamic therapy. ACS Applied Materials & Interfaces. 2022, 14, 37424-37435. (封面邀请，IF：10.383) 17. Bai, Y.,* Li, X.H, Li, M.Q., Shang Q.Q., Yang, J., Fan L.*, Tian W*. Host-guest interactions based supramolecular prodrug self-assemblies for GSH-consumption augmented chemotherapy. Journal of Materials Chemistry B. 2022, 10, 4952-4958. (HOT Papers, 封面邀请，IF: 7.571) 18. Bai, Y.,* Liu, C.P., Yang, J., Liu, C.F.*, Shang Q.Q., Tian W*. Supramolecular self-assemblies based on water-soluble pillar[6]arene and drug-drug conjugates for the combination of chemotherapy. Colloid and Surface B: Biointerfaces. 2022, 217, 112606. (IF: 5.999) 19. Liu, C.F., Li M.Q., Liu C.P., Qiu S., Bai, Y.,* Fan L.*, Tian W*. Supramolecular organometallic drug complex with H2O2 self-provision intensifying intracellular autocatalysis for chemodynamic therapy. Journal of Materials Chemistry B. 2022, 10, 8981–8987. (IF: 7.571) 20. Sai, F.T., Zhang, H.T.,* Qu, J.B., Wang, J.Y., Zhu, X.Z., Bai, Y.,* Ye, P. Multifunctional waterborne polyurethane films: amine-responsive, thermal-driven self-healing and recyclability. Applied Surface Science. 2022, 573, 151526. ( IF: 7.392) 21. Huang, Z., Rao S.H., Fan W.J., Duan Z.Z., Bai, Y.,* Huang X.H., Xu F.F., Li H.* A supramolecular hyperbranched polymer constructed by host‐guest interaction and complementary metal‐coordination interaction. Polymer Chemistry. 2022, 13, 5775-5780 (IF: 5.582) 22. 尚青青，白阳*，杨靖，步怀天. 基于柱芳烃主客体作用构筑的超分子纳米载体及其抗肿瘤性能研究. 化学通报, 2022，3：287-296. 23. 高志亮，南蓓蓓，白阳*，乔红军. 基于环糊精的高交联密度pH响应性水凝胶的制备与性能研究. 高分子通报, 2022, 35:74-86 . 24. Liu, C.F.#, Li M.Q.#, Sun J.X., Li P.X., Bai Y., Zhang J.A., Qian Y.C., Shi M.H., He J., Huo H.B., Pang J., Fan L.*, Tian W*. Cation-π interaction-mediated tumor drug delivery for deep intratumoral penetration and treatment. Advanced Functional Materials. 2022, 2205043. (IF：19.924) 2021年： 25. Wei, K., Zhang H.T.*, Qu J.B., Wang J.Y., Bai, Y.,* Sai F.T. Recyclable shape-memory waterborne polyurethane films based on perylene bisimide modified polycaprolactone diol. Polymers. 2021, 13, 1755.( IF: 4.967) 26. Liu C.F.#, Li M.Q.#, Sun,Li P.X., Bai Y., Pang J., Fan L., Tian W*. Ruthenium (II)-Coordinated supramolecular metallodrug complex realizing oxygen self-supply in situ for overcoming hypoxic tumors. Advanced Functional Materials. 2021, 31, 2105837. (IF：19.924) 27. Yang D*, Gao K.Y., Bai Y, Lei L, Jia T.T., Yang K.D., Xue C H*. Microfluidic synthesis of chitosan-coated magnetic alginate microparticles for controlled and sustained drug delivery. International Journal of Biological Macromolecules. 2021, 182, 639-647. (IF：6.314) 28. Li M.Q., Bai Y., Liu C.F.*, Fan L.*, Tian W*. Supramolecular dual drug nanomicelles for circumvent multidrug resistance. ACS Biomaterials Science & Engineering. 2021, 7, 5515-5523. (IF：4.749) 29. 王杰，李莹，邵亮*，白阳，马忠雷，马建忠. 聚乙烯醇/聚吡咯复合导电水凝胶应变传感器的制备及性能. 高等学校化学学报，2021, 42(3), 929-936. 30. 刘坤，白阳*，杨靖，步怀天*.基于透明质酸构筑的药物递送载体及其应用.化学通报, 2021，3：225-231. 2020年： 31. Bai, Y.,* Liu, C.P., Chen, D., Liu, C.F., Zhuo, L.H., Li, H.*, Bu H.T., Tian W*. β-cyclodextrin-modified hyaluronic acid-based supramolecular self-assemblies for pH- and esterase- dual-responsive drug delivery. Carbohydrate Polymers. 2020, 246, 116654. (IF: 10.723) 32. Bai, Y.,* An, N., Chen, D., Liu, Y.Z., Liu, C.P., Yao, H., Wang, C., Song, X., Tian, W.* Facile construction of shape-regulated β-cyclodextrin-based supramolecular self-assemblies for drug delivery. Carbohydrate Polymers. 2020, 231,115714. (ESI高被引论文，IF: 10.723) 33. Li, H.,* Yang Y., Xu F.F., Chen M.F., Liang T.X., Bai, Y.,* Li R.Q. href="javascript:;" Regulable aggregation-induced emission supramolecular polymer and gel based on self-sorting assembly. Macromolecules. 2020,53,4255-4263. (封面文章，IF：6.057) 34. Liu C.F., Li H.X., Li P.X., Liu C.P., Bai, Y.,* Pang J., Wang J.X., Tian W.* Dual drug-based hyperbranched polymer with methotrexate and chlorambucil moieties for synergistic cancer chemotherapy. Polymer Chemistry. 2020, 11, 5810-5818. (IF: 5.582, Invited paper for the thematic issue of “2021 Polymer Chemistry Pioneering Investigators”) 35. 白阳*, 阎晓晨, 刘彩萍, 姚灏. H型聚合物的合成及性质. 化学进展, 2020, 32(12):1879-1884. (IF:1.013) 36. Shao L*, Li Y, Ma Z, Bai Y, Wang J, Zeng P, Gong P, Shi F, Ji Z, Qiao Y, Xu R, Xu J, Zhang G, Wang C, * Ma J*. A Highly sensitive strain sensor based on stretchable and conductive poly(vinylalcohol)/Phytic acid/ NH2-POSS hydrogel with 3D microporous structure. ACS Applied Materials & Interface. 2020, 23, 26496-26508. (IF: 8.75) 37. Zhuo L, Tang S, Zhao K, Xie F, Bai Y. Green facile fabrication of polyimide by microwave-assisted hydrothermal method and its decomposition dynamic. Journal of Applied Polymer Science. 2020, 20: 48484 (IF: 2.520) 38. 白阳*，辛华，邵彦明，邵亮，马忠雷. 工程教育专业认证背景下的高分子物理教学改革.教育教学论坛，2020, 24, 145-146. 39. 杨靖，白阳*，安娜，刘彩萍，陈香李，步怀天. 基于β-环糊精改性的水溶性苝酰亚胺的合成及其pH响应性研究. 陕西科技大学学报，2020, 1, 81-87. 2019年： 40. Bai, Y.,* Liu, C.P., Xie, F.Y., Ma, R., Zhuo, L.H., Li, N., Tian, W.* Construction of β-cyclodextrin-based supramolecular hyperbranched polymers self-assemblies using AB2-type macromonomer and their application in the drug delivery field. Carbohydrate Polymers. 2019, 213, 411-418. ( IF: 10.723) 41. Bai, Y.,* Liu, C.P., Chen, D., Zhuo, L.H., Bu, H.T., Tian, W.* Morphology-tunable and pH-responsive supramolecular self-assemblies based on AB2-type host-guest-conjugated amphiphilic molecule for controlled drug delivery. Beilstein Journal of Organic Chemistry. 2019, 15, 1925-1932. (IF: 2.622, Invited paper for the thematic issue of “Novel macrocycles- and old ones doing new tricks”) 42. Zhang, Y.J., Bai, Y.,* Li, J.Z., Fu, X.L., Yang, Y.J., Tang, Q.F. Energetic nitrocellulose coating: effective way to decrease sensitivity and modify surface property of HMX particles. Journal of Energetic Materials. 2019, 37, 212-221. ( IF: 2.421) 43. Qian L.*, Yang M., Chen H., Xu Y., Zhang S., Zhou Q., He B., Bai Y., Song W*. Preparation of a poly(ionic liquid)-functionalized cellulose aerogel and its application in protein enrichment and separation. Carbohydrate polymers. 2019, 218, 154-162. (IF: 10.723) 2018年： 44. Bai, Y.,* Liu, C.P., Song, X., Zhuo, L.H., Bu, H.T., Tian, W.* Photo- and pH- dually-responsive β-cyclodextrin-based supramolecular prodrug complexes self-assemblies for programmed drug delivery. Chemistry-an Asian Journal. 2018, 13, 3903-3911. (IF: 4.839) 45. Bai, Y., Xie, F.Y., Tian, W.* Controlled Self-Assembly of Thermo-Responsive Amphiphilic H-Shaped Polymer for Adjustable Drug Release. Chinese Journal of Polymer Science, 2018, 36, 406-416. (IF:3.815, Invited paper for the thematic issue of “Supramolecular self-assembly”) 46. 刘彩萍，白阳* . 环糊精超分子聚合物在药物/基因递送载体领域的研究进展. 化学通报, 2018，4，326-331. 47. 刘彩萍，白阳*. 基于主客体识别作用构筑的聚合物前药胶束及其药物控释性能研究. 陕西科技大学学报，2018，4，63-70. 入职前（2011-2016）： 48. Bai, Y., Fan, X.D.,* Tian, W.*, Liu, T.T., Yao, H., Yang, Z. Morphology transitions of supramolecular hyperbranched polymers induced by double supramolecular driving forces. Polymer Chemistry, 2015, 6: 732-737. (F: 5.687) 49. Bai, Y., Fan, X.D.,* Yao, H., Yang, Z., Liu, T.T., Zhang, H.T., Tian, W*. Probing into the Supramolecular Driving Force of an Amphiphilic β-Cyclodextrin Dimer in Various Solvents: Host–Guest Recognition or Hydrophilic–Hydrophobic Interaction? Journal of Physical Chemistry B, 2015, 119: 11893-11899. (IF:3.302) 50. 白阳，范晓东*，田威*，姚灏，范伟伟，刘婷婷，党静，朱秀忠. 星型三杂臂共聚物的合成及其自组装性能研究. 高分子学报, 2014, 6: 851-859. (IF:0.639) 51. Bai, Y., Fan, X.D.,* Tian, W.*, Yao, H., Zhuo, L.H., Zhang, H.T., Yang, Z. Synthesis and thermally-triggered self-assembly behaviors of a dumbbell-shaped polymer carrying β-cyclodextrin at branch point. Polymer, 2013, 54: 3566-3573. (IF: 3.766) 52. Bai, Y., Fan, X.D.,* Tian, W.*, Mu, C.G., Yang, Z., Fan, W.W., Zhang, H.T., & Zhang, W.B. Large complex micelles formed from amphiphilic H-shaped terpolymers with adjustable block ratio by ultrasonic vibration. Polymer, 2013, 54: 1734-1738. (2013IF: 3.766) 53. 白阳，范晓东*，穆承广，杨臻，王丹，张海涛. 含环糊精链节的拓扑高分子.化学进展, 2013, 2/3: 363-369. (2013IF: 0.894) 54. Yang Y*, Bai Y., Zhao F, Yao E, Yi J, Xuan C, Chen S. Effects of metal organic framework Fe-BTC on the thermal decomposition of ammonium perchlorate. RSC Advances, 2016, 6, 67308-67314. (IF: 3.108) 55. Liu T, Tian W*, Song Y, Bai Y, Wei P, Yao H, Yan H. Reversible self-assembly of backbone-thermoresponsive long chain hyperbranched poly(N-isopropyl acrylamide). Polymers, 2016, 8, 33-47. 56. Zhuo L*, Kou K, Bai Y, Wang Y, Wu G. Study of thermal decomposition kinetics for polyimides based on 2,6-bis(4-amino- phenyl)-4-(4-(4-aminophenoxy) phenyl) pyridine. High Performance Polymers, 2016, 28(4): 390-400. 57. Zhuo L*, Kou K, Bai Y, Chao M, Wang Y. Influence of terminating triamine by phthalic anhydride on polyimides’ properties. 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An H-shaped Polymer bonding β-cyclodextrin at branch points, synthesis and influences of attached β-cyclodextrins on physical properties. Journal of Polymer Science Part A: Polymer Chemistry. 2013, 51(6): 1405-1416. 67. Mu, C, Fan X*, Tian W*, Bai Y, Yang Z, Fan W, Chen H. Synthesis and stimulus-responsive micellization of a well-defined H-shaped terpolymer. Polymer Chemistry, 2012, 3(12): 3330-3339. 68. Mu C, Fan X*, Tian W*, Bai Y, Zhou X. Miktoarm star Polymers with poly(N- isopropylacrylamide) or poly(oligo(ethylene glycol) methacrylate) as building blocks, synthesis and comparison of thermally- responsive behaviors. Polymer Chemistry, 2012, 3(5): 1137-1149. 69. 穆承广，范晓东*，田威*，白阳，南江琨，马托梅，杨光.基于星型杂臂环糊精聚合物的纳米胶束：构筑与包合特性. 高等学校化学学报，2011,8,1896-1903. 70. 刘晓军, 李吉祯, 张正中, 邓重清, 白阳, 屈蓓. 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